RNA Details
Disease Name
cataract
Tissue
eye
RNA Symbol
mir-30a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
q-PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
SNAI1
Pathway
NA
PubMed ID
Title
MicroRNA-30a Regulation of Epithelial-Mesenchymal Transition in Diabetic Cataracts Through Targeting SNAI1
Year
2017
Function
"It is concluded that emt is involved in human diabetic cataract, and upregulation of mir-30a can repress emt through its targeting of snai1 in lens epithelial cells, which make mir-30a a novel target of therapeutic intervention for human diabetic cataract."